Androgen Receptor Signaling in Bladder Cancer.
Ontology highlight
ABSTRACT:
SUBMITTER: Li P
PROVIDER: S-EPMC5332943 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Publications
Androgen Receptor Signaling in Bladder Cancer.
Li Peng P Chen Jinbo J Miyamoto Hiroshi H
Cancers 20170222 2
Emerging preclinical findings have indicated that steroid hormone receptor signaling plays an important role in bladder cancer outgrowth. In particular, androgen-mediated androgen receptor signals have been shown to correlate with the promotion of tumor development and progression, which may clearly explain some sex-specific differences in bladder cancer. This review summarizes and discusses the available data, suggesting the involvement of androgens and/or the androgen receptor pathways in urot ...[more]
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