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Using 3dRPC for RNA-protein complex structure prediction.


ABSTRACT: 3dRPC is a computational method designed for three-dimensional RNA-protein complex structure prediction. Starting from a protein structure and a RNA structure, 3dRPC first generates presumptive complex structures by RPDOCK and then evaluates the structures by RPRANK. RPDOCK is an FFT-based docking algorithm that takes features of RNA-protein interactions into consideration, and RPRANK is a knowledge-based potential using root mean square deviation as a measure. Here we give a detailed description of the usage of 3dRPC. The source code is available at http://biophy.hust.edu.cn/3dRPC.html.

SUBMITTER: Huang Y 

PROVIDER: S-EPMC5334405 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Using 3dRPC for RNA-protein complex structure prediction.

Huang Yangyu Y   Li Haotian H   Xiao Yi Y  

Biophysics reports 20160101 5


3dRPC is a computational method designed for three-dimensional RNA-protein complex structure prediction. Starting from a protein structure and a RNA structure, 3dRPC first generates presumptive complex structures by RPDOCK and then evaluates the structures by RPRANK. RPDOCK is an FFT-based docking algorithm that takes features of RNA-protein interactions into consideration, and RPRANK is a knowledge-based potential using root mean square deviation as a measure. Here we give a detailed descriptio  ...[more]

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