Ontology highlight
ABSTRACT:
SUBMITTER: Gourinchas G
PROVIDER: S-EPMC5336353 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Gourinchas Geoffrey G Etzl Stefan S Göbl Christoph C Vide Uršula U Madl Tobias T Winkler Andreas A
Science advances 20170303 3
Nature has evolved an astonishingly modular architecture of covalently linked protein domains with diverse functionalities to enable complex cellular networks that are critical for cell survival. The coupling of sensory modules with enzymatic effectors allows direct allosteric regulation of cellular signaling molecules in response to diverse stimuli. We present molecular details of red light-sensing bacteriophytochromes linked to cyclic dimeric guanosine monophosphate-producing diguanylyl cyclas ...[more]