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Cardiovascular Effects of Stimulant and Non-Stimulant Medication for Children and Adolescents with ADHD: A Systematic Review and Meta-Analysis of Trials of Methylphenidate, Amphetamines and Atomoxetine.


ABSTRACT:

SUBMITTER: Hennissen L 

PROVIDER: S-EPMC5336546 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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Cardiovascular Effects of Stimulant and Non-Stimulant Medication for Children and Adolescents with ADHD: A Systematic Review and Meta-Analysis of Trials of Methylphenidate, Amphetamines and Atomoxetine.

Hennissen Leonie L   Bakker Mireille J MJ   Banaschewski Tobias T   Carucci Sara S   Coghill David D   Danckaerts Marina M   Dittmann Ralf W RW   Hollis Chris C   Kovshoff Hanna H   McCarthy Suzanne S   Nagy Peter P   Sonuga-Barke Edmund E   Wong Ian C K IC   Zuddas Alessandro A   Rosenthal Eric E   Buitelaar Jan K JK  

CNS drugs 20170301 3


<h4>Background</h4>Many children and adolescents with attention deficit/hyperactivity disorder (ADHD) are treated with stimulant and non-stimulant medication. ADHD medication may be associated with cardiovascular effects. It is important to identify whether mean group effects translate into clinically relevant increases for some individual patients, and/or increase the risk for serious cardiovascular adverse events such as stroke or sudden death.<h4>Objectives</h4>To evaluate potential cardiovas  ...[more]

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