Ontology highlight
ABSTRACT:
SUBMITTER: Huang B
PROVIDER: S-EPMC5337363 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Huang Boyuan B Zhang Hongbo H Gu Lijuan L Ye Bainxin B Jian Zhihong Z Stary Creed C Xiong Xiaoxing X
Journal of immunology research 20170219
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults. Patients with GBM have poor outcomes, even with the current gold-standard first-line treatment: maximal safe resection combined with radiotherapy and temozolomide chemotherapy. Accumulating evidence suggests that advances in antigen-specific cancer vaccines and immune checkpoint blockade in other advanced tumors may provide an appealing promise for immunotherapy in glioma. The future of therapy for GBM will ...[more]