Ontology highlight
ABSTRACT:
SUBMITTER: Dongre R
PROVIDER: S-EPMC5338232 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Dongre Ramachandra R Folkers Gert E GE Gualerzi Claudio O CO Boelens Rolf R Wienk Hans H
Protein science : a publication of the Protein Society 20160717 9
Bacterial translation initiation factor IF2 complexed with GTP binds to the 30S ribosomal subunit, promotes ribosomal binding of fMet-tRNA, and favors the joining of the small and large ribosomal subunits yielding a 70S initiation complex ready to enter the translation elongation phase. Within the IF2 molecule subdomain G3, which is believed to play an important role in the IF2-30S interaction, is positioned between the GTP-binding G2 and the fMet-tRNA binding C-terminal subdomains. In this stud ...[more]