Ontology highlight
ABSTRACT:
SUBMITTER: Bucks SA
PROVIDER: S-EPMC5338920 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Bucks Stephanie A SA Cox Brandon C BC Vlosich Brittany A BA Manning James P JP Nguyen Tot B TB Stone Jennifer S JS
eLife 20170306
Vestibular hair cells in the inner ear encode head movements and mediate the sense of balance. These cells undergo cell death and replacement (turnover) throughout life in non-mammalian vertebrates. However, there is no definitive evidence that this process occurs in mammals. We used fate-mapping and other methods to demonstrate that utricular type II vestibular hair cells undergo turnover in adult mice under normal conditions. We found that supporting cells phagocytose both type I and II hair c ...[more]