A PRISMA-compliant meta-analysis of MDM4 genetic variants and cancer susceptibility.
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ABSTRACT:
SUBMITTER: Zhai Y
PROVIDER: S-EPMC5342025 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Publications
A PRISMA-compliant meta-analysis of MDM4 genetic variants and cancer susceptibility.
Zhai Yajing Y Dai Zhijun Z He Hairong H Gao Fan F Yang Lihong L Dong Yalin Y Lu Jun J
Oncotarget 20161101 45
Molecular epidemiological research suggests that mouse double minute 4 (MDM4) polymorphisms may be associated with cancer susceptibility, but results remain controversial. To derive a more precise evaluation, we performed a PRISMA compliant meta-analysis focused on five single nucleotide polymorphisms (rs11801299, rs1380576, rs10900598, rs1563828, and rs4245739) of MDM4. Overall, 23 studies involving 22,218 cases and 55,033 controls were analyzed. The results showed that rs4245739 was significan ...[more]
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