Prognostic significance of PLIN1 expression in human breast cancer.
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ABSTRACT:
SUBMITTER: Zhou C
PROVIDER: S-EPMC5342357 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Publications
Prognostic significance of PLIN1 expression in human breast cancer.
Zhou Cefan C Wang Ming M Zhou Li L Zhang Yi Y Liu Weiyong W Qin Wenying W He Rong R Lu Yang Y Wang Yefu Y Chen Xing-Zhen XZ Tang Jingfeng J
Oncotarget 20160801 34
Breast cancer is a heterogeneous disease associated with diverse clinical, biological and molecular features, presenting huge challenges for prognosis and treatment. Here we found that perilipin-1 (PLIN1) mRNA expression is significantly downregulated in human breast cancer. Kaplan-Meier analysis indicated that patients presenting with reduced PLIN1 expression exhibited poorer overall metastatic relapse-free survival (p = 0.03). Further Cox proportional hazard models analysis revealed that the r ...[more]
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