Ontology highlight
ABSTRACT:
SUBMITTER: Ma Y
PROVIDER: S-EPMC5342394 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Ma Yihan Y Xu Peiqi P Mi Yanjun Y Wang Wenyi W Pan Xiaoyan X Wu Xiaoting X He Qi Q Liu Hongming H Tang Weiwei W An Hanxiang H
Oncotarget 20160801 34
Based on recognition of driver mutations, treatment paradigm for non-small-cell lung cancer (NSCLC) patients has been shifted. However, recently exon 19 deletion mutation (del19) of epidermal growth factor receptor (EGFR) clearly shows better clinical benefit over single-point substitution mutation L858R in exon 21 (L858R). The aim of this study was to investigate the difference by analyzing the expression of plasma microRNAs (miRNAs) of NSCLC patients with EGFR mutation del19 or L858R. MiRNA mi ...[more]