Ontology highlight
ABSTRACT:
SUBMITTER: Thakur MK
PROVIDER: S-EPMC5342611 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Thakur Manish K MK Wozniak Antoinette J AJ
Lung Cancer (Auckland, N.Z.) 20170213
The treatment options for metastatic non-small-cell lung cancer (NSCLC) have expanded dramatically in the last 10 years with the discovery of newer drugs and targeted therapy. Epidermal growth factor receptor (EGFR), when aberrantly activated, promotes cell growth and contributes in various ways to the malignant process. EGFR has become an important therapeutic target in a variety of malignancies. Small-molecule tyrosine kinase inhibitors (TKIs) of EGFR are being used to treat advanced NSCLC and ...[more]