Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC5343029 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Zhang Yong Y Qi Zhimin Z Liu Yan Y He Wenqi W Yang Cheng C Wang Quan Q Dong Jing J Deng Xuming X
Frontiers in microbiology 20170309
Shiga-like toxin-producing <i>Escherichia coli</i> (STEC) O157:H7 poses grave challenges to public health by its ability to cause severe colonic diseases and renal failure in both human and animals. Shiga-like toxins are the major pathogenic factor for some highly virulent <i>E. coli</i> expecially Shiga-like toxin 2. Conventional treatments such as antibiotics can facilitate the release of the toxin thus potentially exacerbate the diseases. Small molecule inhibitors and antibodies capable of ne ...[more]