Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC5343500 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Nature communications 20170306
Metal carbenes are often proposed as reactive intermediates in the late transition metal-catalysed transformations of alkynes. Owing to their high reactivity, however, isolation and structural characterization of metal carbene intermediates in these transformations has remained unknown. Herein, we report the isolation of two acyclic gold and copper carbene intermediates in either Au(I)- or Cu(I)-catalysed cyclization of N-alkynyl formamidines through five-exo-dig cyclization. X-ray diffraction, ...[more]