Ontology highlight
ABSTRACT:
SUBMITTER: Ribela MT
PROVIDER: S-EPMC5343769 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Ribela Maria Teresa C P MT Damiani Renata R Silva Felipe D FD Lima Eliana R ER Oliveira João E JE Peroni Cibele N CN Torjesen Peter A PA Soares Carlos R CR Bartolini Paolo P
International journal of molecular sciences 20170203 2
Human thyrotropin (hTSH) is a glycoprotein with three potential glycosylation sites: two in the α-subunit and one in the β-subunit. These sites are not always occupied and occupancy is frequently neglected in glycoprotein characterization, even though it is related to folding, trafficking, initiation of inflammation and host defense, as well as congenital disorders of glycosylation (CDG). For the first time <i>N</i>-glycoprofiling analysis was applied to the site-occupancy determination of two n ...[more]