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Empirically derived personality subtyping for predicting clinical symptoms and treatment response in bulimia nervosa.


ABSTRACT: Evidence suggests that eating disorder subtypes reflecting under-controlled, over-controlled, and low psychopathology personality traits constitute reliable phenotypes that differentiate treatment response. This study is the first to use statistical analyses to identify these subtypes within treatment-seeking individuals with bulimia nervosa (BN) and to use these statistically derived clusters to predict clinical outcomes.Using variables from the Dimensional Assessment of Personality Pathology-Basic Questionnaire, K-means cluster analyses identified under-controlled, over-controlled, and low psychopathology subtypes within BN patients (n?=?80) enrolled in a treatment trial. Generalized linear models examined the impact of personality subtypes on Eating Disorder Examination global score, binge eating frequency, and purging frequency cross-sectionally at baseline and longitudinally at end of treatment (EOT) and follow-up. In the longitudinal models, secondary analyses were conducted to examine personality subtype as a potential moderator of response to Cognitive Behavioral Therapy-Enhanced (CBT-E) or Integrative Cognitive-Affective Therapy for BN (ICAT-BN).There were no baseline clinical differences between groups. In the longitudinal models, personality subtype predicted binge eating (p?=?0.03) and purging (p?=?0.01) frequency at EOT and binge eating frequency at follow-up (p?=?0.045). The over-controlled group demonstrated the best outcomes on these variables. In secondary analyses, there was a treatment by subtype interaction for purging at follow-up (p?=?0.04), which indicated a superiority of CBT-E over ICAT-BN for reducing purging among the over-controlled group.Empirically derived personality subtyping appears to be a valid classification system with potential to guide eating disorder treatment decisions. © 2016 Wiley Periodicals, Inc.(Int J Eat Disord 2017; 50:506-514).

SUBMITTER: Haynos AF 

PROVIDER: S-EPMC5344779 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature

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Empirically derived personality subtyping for predicting clinical symptoms and treatment response in bulimia nervosa.

Haynos Ann F AF   Pearson Carolyn M CM   Utzinger Linsey M LM   Wonderlich Stephen A SA   Crosby Ross D RD   Mitchell James E JE   Crow Scott J SJ   Peterson Carol B CB  

The International journal of eating disorders 20160909 5


<h4>Objective</h4>Evidence suggests that eating disorder subtypes reflecting under-controlled, over-controlled, and low psychopathology personality traits constitute reliable phenotypes that differentiate treatment response. This study is the first to use statistical analyses to identify these subtypes within treatment-seeking individuals with bulimia nervosa (BN) and to use these statistically derived clusters to predict clinical outcomes.<h4>Methods</h4>Using variables from the Dimensional Ass  ...[more]

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