Ontology highlight
ABSTRACT:
SUBMITTER: Adamiak M
PROVIDER: S-EPMC5346113 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Adamiak Mateusz M Abdelbaset-Ismail Ahmed A Moore Joseph B JB Zhao J J Abdel-Latif Ahmed A Wysoczynski Marcin M Ratajczak Mariusz Z MZ
Stem cell reviews and reports 20170201 1
Nitric oxide (NO) is a gaseous free radical molecule involved in several biological processes related to inflammation, tissue damage, and infections. Based on reports that NO inhibits migration of granulocytes and monocytes, we became interested in the role of inducible NO synthetase (iNOS) in pharmacological mobilization of hematopoietic stem/progenitor cells (HSPCs) from bone marrow (BM) into peripheral blood (PB). To address the role of NO in HSPC trafficking, we upregulated or downregulated ...[more]