Ontology highlight
ABSTRACT:
SUBMITTER: Jo HS
PROVIDER: S-EPMC5346322 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Jo Hyo Sang HS Kim Duk-Soo DS Ahn Eun Hee EH Kim Dae Won DW Shin Min Jea MJ Cho Su Bin SB Park Jung Hwan JH Lee Chi Hern CH Yeo Eun Ji EJ Choi Yeon Joo YJ Yeo Hyeon Ji HJ Chung Christine Seok Young CS Cho Sung-Woo SW Han Kyu Hyung KH Park Jinseu J Eum Won Sik WS Choi Soo Young SY
BMB reports 20161101 11
Oxidative stress is closely associated with various diseases and is considered to be a major factor in ischemia. NAD(P)H:quinone oxidoreductase 1 (NQO1) protein is a known antioxidant protein that plays a protective role in various cells against oxidative stress. We therefore investigated the effects of cell permeable Tat-NQO1 protein on hippocampal HT-22 cells, and in an animal ischemia model. The Tat-NQO1 protein transduced into HT-22 cells, and significantly inhibited against hydrogen peroxid ...[more]