Ontology highlight
ABSTRACT:
SUBMITTER: Lukamowicz-Rajska M
PROVIDER: S-EPMC5346651 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Lukamowicz-Rajska Magdalena M Mittmann Christiane C Prummer Michael M Zhong Qing Q Bedke Jens J Hennenlotter Jörg J Stenzl Arnulf A Mischo Axel A Bihr Svenja S Schmidinger Manuela M Vogl Ursula U Blume Iris I Karlo Christoph C Schraml Peter P Moch Holger H
Oncotarget 20161101 48
A number of treatments targeting VEGF or mTOR pathways have been approved for metastatic clear cell Renal Cell Carcinoma (ccRCC), but the majority of patients show disease progression after first line therapy with a very low rate of complete or long-term responders. It has been shown that miRs may play a role in prediction of treatment response in various cancer types. The aim of our study was to identify a miR signature predictive for RCC patients' response to antiangiogenic tyrosine kinase inh ...[more]