Ontology highlight
ABSTRACT:
SUBMITTER: Lu X
PROVIDER: S-EPMC5347003 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Lu Xiaolu X Shi Xueyao X Wu Gege G Wu Tiantian T Qin Rui R Wang Yi Y
Scientific reports 20170313
The split G-quadruplex DNAzyme has emerged as a valuable tool for visual DNA detection. Here, we successfully integrated colorimetric split G-quadruplex DNAzyme assay with nucleic acid sequence-based amplification to generate a novel detection approach, allowing visual and rapid detection for the RNA of Shimen and HCLV strains of Classic Swine Fever Virus (CSFV). CSFV is a RNA virus that causes a highly contagious disease in domestic pigs and wild boar. With this method, we were able to detect a ...[more]