Ontology highlight
ABSTRACT:
SUBMITTER: Wu C
PROVIDER: S-EPMC5347676 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Wu Chongyang C Zhang Ying Y Shen Qiaoyan Q Zhou Zhe Z Liu Weishuai W Hua Jinlian J
Oncotarget 20161201 50
The decline of quantity and quality of sperm are correlated with the increasing age and some anti-cancer compounds such as busulfan. Previous studies have shown that Resveratrol (Res) inhibits tumorigenesis and metastasis of many cancers including mammary tumor, prostate and pancreatic cancers. It acts as anti-age in mouse and human, however, little is known about its protective effect on aged spermatogonial stem cells (SSCs). Here, we investigated the effects of Res in vitro on SSCs using C18-4 ...[more]