Dataset Information

Stochastic and Differential Activation of σ^B and PrfA in Listeria monocytogenes at the Single Cell Level under Different Environmental Stress Conditions.

ABSTRACT: During host infection, the foodborne pathogen Listeria monocytogenes must sense and respond to rapidly changing environmental conditions. Two transcriptional regulators, the alternative sigma factor B (σ^B) and the Positive Regulatory Factor A (PrfA), are key contributors to the transcriptomic responses that enable bacterial survival in the host gastrointestinal tract and invasion of host duodenal cells. Increases in temperature and osmolarity induce activity of these proteins; such conditions may be encountered in food matrices as well as within the host gastrointestinal tract. Differences in PrfA and σ^B activity between individual cells might affect the fate of a cell during host invasion, therefore, we hypothesized that PrfA and σ^B activities diffe

SUBMITTER: Guldimann C

PROVIDER: S-EPMC5349113 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Dataset Information

Stochastic and Differential Activation of σ^B and PrfA in Listeria monocytogenes at the Single Cell Level under Different Environmental Stress Conditions.

OmicsDI is part of the ELIXIR infrastructure

Tweets

Dataset Information

Stochastic and Differential Activation of σB and PrfA in Listeria monocytogenes at the Single Cell Level under Different Environmental Stress Conditions.

OmicsDI is part of the ELIXIR infrastructure

Tweets

Stochastic and Differential Activation of σ^B and PrfA in Listeria monocytogenes at the Single Cell Level under Different Environmental Stress Conditions.