Ontology highlight
ABSTRACT:
SUBMITTER: Fernandez-Twinn DS
PROVIDER: S-EPMC5349590 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Fernandez-Twinn Denise S DS Gascoin Geraldine G Musial Barbara B Carr Sarah S Duque-Guimaraes Daniella D Blackmore Heather L HL Alfaradhi Maria Z MZ Loche Elena E Sferruzzi-Perri Amanda N AN Fowden Abigail L AL Ozanne Susan E SE
Scientific reports 20170314
The prevalence of obesity during pregnancy continues to increase at alarming rates. This is concerning as in addition to immediate impacts on maternal wellbeing, obesity during pregnancy has detrimental effects on the long-term health of the offspring through non-genetic mechanisms. A major knowledge gap limiting our capacity to develop intervention strategies is the lack of understanding of the factors in the obese mother that mediate these epigenetic effects on the offspring. We used a mouse m ...[more]