Ontology highlight
ABSTRACT:
SUBMITTER: Flannigan KL
PROVIDER: S-EPMC5350071 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Flannigan K L KL Ngo V L VL Geem D D Harusato A A Hirota S A SA Parkos C A CA Lukacs N W NW Nusrat A A Gaboriau-Routhiau V V Cerf-Bensussan N N Gewirtz A T AT Denning T L TL
Mucosal immunology 20160914 3
Specific components of the intestinal microbiota are capable of influencing immune responses such that a mutualistic relationship is established. In mice, colonization with segmented filamentous bacteria (SFB) induces T-helper-17 (Th17) cell differentiation in the intestine, yet the effector functions of interleukin (IL)-17A in response to SFB remain incompletely understood. Here we report that colonization of mice with SFB-containing microbiota induced IL-17A- and CXCR2-dependent recruitment of ...[more]