Ontology highlight
ABSTRACT:
SUBMITTER: Arthaut LD
PROVIDER: S-EPMC5351967 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Arthaut Louis-David LD Jourdan Nathalie N Mteyrek Ali A Procopio Maria M El-Esawi Mohamed M d'Harlingue Alain A Bouchet Pierre-Etienne PE Witczak Jacques J Ritz Thorsten T Klarsfeld André A Birman Serge S Usselman Robert J RJ Hoecker Ute U Martino Carlos F CF Ahmad Margaret M
PloS one 20170315 3
Cryptochromes are evolutionarily conserved blue-light absorbing flavoproteins which participate in many important cellular processes including in entrainment of the circadian clock in plants, Drosophila and humans. Drosophila melanogaster cryptochrome (DmCry) absorbs light through a flavin (FAD) cofactor that undergoes photoreduction to the anionic radical (FAD•-) redox state both in vitro and in vivo. However, recent efforts to link this photoconversion to the initiation of a biological respons ...[more]