Ontology highlight
ABSTRACT:
SUBMITTER: Jiang CL
PROVIDER: S-EPMC5352062 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Jiang Cheng-Lan CL He Shui-Wang SW Zhang Yun-Dong YD Duan He-Xian HX Huang Tao T Huang Yun-Chao YC Li Gao-Feng GF Wang Ping P Ma Li-Ju LJ Zhou Guang-Biao GB Zhou Guang-Biao GB Cao Yi Y
Oncotarget 20170101 1
The lung cancer incidence in the Xuanwei and neighboring region, Yunnan, China, is among the highest in China and is attributed to severe air pollution with high benzo(a)pyrene levels. We systematically and comparatively analyzed DNA methylation alterations at genome and gene levels in Xuanwei lung cancer tissues and cell lines, as well as benzo(a)pyrene-treated cells and mouse samples. We obtained a comprehensive dataset of genome-wide cytosine-phosphate-guanine island methylation in air pollut ...[more]