Ontology highlight
ABSTRACT:
SUBMITTER: Tzouvelekis A
PROVIDER: S-EPMC5352520 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Tzouvelekis Argyris A Herazo-Maya Jose D JD Slade Martin M Chu Jen-Hwa JH Deiuliis Giuseppe G Ryu Changwan C Li Qin Q Sakamoto Koji K Ibarra Gabriel G Pan Hongyi H Gulati Mridu M Antin-Ozerkis Danielle D Herzog Erica L EL Kaminski Naftali N
Respirology (Carlton, Vic.) 20161019 3
<h4>Background and objective</h4>Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor prognosis and variable clinical course. Although matrix metalloproteinase-7 (MMP-7) is emerging as an important IPF biomarker, reproducibility across studies is unclear. We aimed to determine whether a previously reported prognostic threshold for MMP-7 was predictive of mortality in an independent cohort of IPF patients.<h4>Methods</h4>MMP-7 concentrations obtained from heparinized plasma samp ...[more]