ITPR3 gene haplotype is associated with cervical squamous cell carcinoma risk in Taiwanese women.
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ABSTRACT:
SUBMITTER: Yang YC
PROVIDER: S-EPMC5354643 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Publications
ITPR3 gene haplotype is associated with cervical squamous cell carcinoma risk in Taiwanese women.
Yang Yuh-Cheng YC Chang Tzu-Yang TY Chen Tze-Chien TC Lin Wen-Shan WS Chang Shih-Chuan SC Lee Yann-Jinn YJ
Oncotarget 20170201 6
Host immunogenetic background plays an important role in human papillomavirus (HPV) infection and cervical cancer development. Inositol 1,4,5-triphosphate receptor type 3 (ITPR3) is essential for both immune activation and cancer pathogenesis. We aim to investigate if ITPR3 genetic polymorphisms are associated with the risk of cervical cancer in Taiwanese women. ITPR3 rs3748079 A/G and rs2229634 C/T polymorphisms were genotyped in a hospital-based study of 462 women with cervical squamous cell c ...[more]
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