Ontology highlight
ABSTRACT:
SUBMITTER: Kazanis I
PROVIDER: S-EPMC5355571 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Kazanis Ilias I Evans Kimberley A KA Andreopoulou Evangelia E Dimitriou Christina C Koutsakis Christos C Karadottir Ragnhildur Thora RT Franklin Robin J M RJM
Stem cell reports 20170209 3
Two populations of oligodendrogenic progenitors co-exist within the corpus callosum (CC) of the adult mouse. Local, parenchymal oligodendrocyte progenitor cells (pOPCs) and progenitors generated in the subependymal zone (SEZ) cytogenic niche. pOPCs are committed perinatally and retain their numbers through self-renewing divisions, while SEZ-derived cells are relatively "young," being constantly born from neural stem cells. We compared the behavior of these populations, labeling SEZ-derived cells ...[more]