Ontology highlight
ABSTRACT:
SUBMITTER: Palmenberg AC
PROVIDER: S-EPMC5355607 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Journal of virology 20170313 7
Human rhinoviruses (RVs) of the A, B, and C species are defined agents of the common cold. But more than that, RV-A and RV-C are the dominant causes of hospitalization category infections in young children, especially those with asthma. The use of cadherin-related family member 3 (CDHR3) by RV-C as its cellular receptor creates a direct phenotypic link between human genetics (G versus A alleles cause Cys529 versus Tyr529 protein variants) and the efficiency with which RV-C can infect cells. With ...[more]