Ontology highlight
ABSTRACT:
SUBMITTER: Lee BP
PROVIDER: S-EPMC5356331 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Lee Benjamin P BP Burić Ivana I George-Pandeth Anupriya A Flurkey Kevin K Harrison David E DE Yuan Rong R Peters Luanne L LL Kuchel George A GA Melzer David D Harries Lorna W LW
Scientific reports 20170317
MicroRNAs (miRNAs) are small non-coding RNA species that have been shown to have roles in multiple processes that occur in higher eukaryotes. They act by binding to specific sequences in the 3' untranslated region of their target genes and causing the transcripts to be degraded by the RNA-induced silencing complex (RISC). MicroRNAs have previously been reported to demonstrate altered expression in several aging phenotypes such as cellular senescence and age itself. Here, we have measured the exp ...[more]