IGFBP6 is a novel nasopharyngeal carcinoma prognostic biomarker.
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ABSTRACT:
SUBMITTER: Chen Q
PROVIDER: S-EPMC5356544 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
IGFBP6 is a novel nasopharyngeal carcinoma prognostic biomarker.
Chen Qiuyan Q Qin Siyuan S Liu Yang Y Hong Minghuang M Qian Chao-Nan CN Keller Evan T ET Zhang Jian J Lu Yi Y
Oncotarget 20161001 42
Insulin-like growth factor binding proteins (IGFBPs) play critical roles in carcinogenesis. This study assessed the impact of IGFBP6 on the progression of nasopharyngeal carcinoma (NPC). Using immunohistochemical analysis, we found that IGFBP6 was differentially expressed in primary malignant NPC tissues. Clinical samples were divided into two groups: IGFBP6(+) and IGFBP6(-). Five years of follow-up revealed that overall survival and distant metastasis-free survival rates were significantly high ...[more]
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