Ontology highlight
ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC5356575 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Li Yunchao Y Zhao Chunhua C Yu Zhibin Z Chen Jiarui J She Xiaoling X Li Peiyao P Liu Changhong C Zhang Yan Y Feng Jianbo J Fu Haijuan H Wang Bing B Kuang Lei L Li Lei L Lv Guohua G Wu Minghua M
Oncotarget 20161001 42
Osteosarcoma (OS) is the most common primary bone malignancy with a poor prognosis for all races and both sexes. In this study, we found that miR-381 is a positive prognosis factor for OS patients that OS patients with a low expression of miR-381 had a longer survival time after surgical intervention, and miR-381 expression promotes MG-63 cell proliferation and cell invasion ability. Our results also showed a strong negative correlation between the expression of miR-381 and LRRC4 (brain relative ...[more]