Ontology highlight
ABSTRACT:
SUBMITTER: Kumada H
PROVIDER: S-EPMC5357479 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Kumada Hiromitsu H Suzuki Yoshiyuki Y Karino Yoshiyasu Y Chayama Kazuaki K Kawada Norifumi N Okanoue Takeshi T Itoh Yoshito Y Mochida Satoshi S Toyoda Hidenori H Yoshiji Hitoshi H Takaki Shintaro S Yatsuzuka Naoyoshi N Yodoya Etsuo E Iwasa Takashi T Fujimoto Go G Robertson Michael N MN Black Stuart S Caro Luzelena L Wahl Janice J
Journal of gastroenterology 20161121 4
<h4>Background</h4>Elbasvir (EBR) in combination with grazoprevir (GZR) has demonstrated efficacy in patients with hepatitis C virus (HCV) infections in trials primarily conducted in the USA and Europe. We investigated the safety and efficacy of EBR in combination with GZR in Japanese patients with chronic HCV infection, with or without cirrhosis.<h4>Methods</h4>The study was conducted in two parts. In part 1, noncirrhotic patients were randomized 1:1 to receive EBR (50 mg) in combination with G ...[more]