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Data on chemical activation of Wnt/?-catenin during axolotl limb regeneration.

ABSTRACT: Limb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein)/?-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017) [1]. The data revealed that active ?-catenin protein was present during limb regeneration in some Leydig cells in the epithelium; after the chemical treatment, it was observed in more Leydig cells. In addition, the chemical agonist of Wnt generated distinct limb malformation.

SUBMITTER: Wischin S

PROVIDER: S-EPMC5357679 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

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Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration.

Wischin Sabina S Castañeda-Patlán Cristina C Robles-Flores Martha M Chimal-Monroy Jesús J

Data in brief 20170303

Limb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein)/β-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017) [1]. The data revealed that active β-catenin protein was present during limb regeneration in some Leydig cells in the epithelium; after the chemical treatment, it was observed in more Leydig cells. In addition, the chemical agonist of Wnt generated distinct limb malformation. ...[more]

PMID: 28349103

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