Ontology highlight
ABSTRACT:
SUBMITTER: Zhan T
PROVIDER: S-EPMC5357762 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Wnt signaling is one of the key cascades regulating development and stemness, and has also been tightly associated with cancer. The role of Wnt signaling in carcinogenesis has most prominently been described for colorectal cancer, but aberrant Wnt signaling is observed in many more cancer entities. Here, we review current insights into novel components of Wnt pathways and describe their impact on cancer development. Furthermore, we highlight expanding functions of Wnt signaling for both solid an ...[more]