Ontology highlight
ABSTRACT:
SUBMITTER: Ruiz-Carpio V
PROVIDER: S-EPMC5361179 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Ruiz-Carpio Vicente V Sandoval Pilar P Aguilera Abelardo A Albar-Vizcaíno Patricia P Perez-Lozano María Luisa ML González-Mateo Guadalupe T GT Acuña-Ruiz Adrián A García-Cantalejo Jesús J Botías Pedro P Bajo María Auxiliadora MA Selgas Rafael R Sánchez-Tomero José Antonio JA Passlick-Deetjen Jutta J Piecha Dorothea D Büchel Janine J Steppan Sonja S López-Cabrera Manuel M
Scientific reports 20170322
Peritoneal dialysis (PD) is an effective renal replacement therapy, but a significant proportion of patients suffer PD-related complications, which limit the treatment duration. Mesothelial-to-mesenchymal transition (MMT) contributes to the PD-related peritoneal dysfunction. We analyzed the genetic reprograming of MMT to identify new biomarkers that may be tested in PD-patients. Microarray analysis revealed a partial overlapping between MMT induced in vitro and ex vivo in effluent-derived mesoth ...[more]