Ontology highlight
ABSTRACT:
SUBMITTER: Ishemgulova A
PROVIDER: S-EPMC5362078 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Ishemgulova Aygul A Butenko Anzhelika A Kortišová Lucie L Boucinha Carolina C Grybchuk-Ieremenko Anastasiia A Morelli Karina A KA Tesařová Martina M Kraeva Natalya N Grybchuk Danyil D Pánek Tomáš T Flegontov Pavel P Lukeš Julius J Votýpka Jan J Pavan Márcio Galvão MG Opperdoes Fred R FR Spodareva Viktoria V d'Avila-Levy Claudia M CM Kostygov Alexei Yu AY Yurchenko Vyacheslav V
PloS one 20170322 3
In the present work, we investigated molecular mechanisms governing thermal resistance of a monoxenous trypanosomatid Crithidia luciliae thermophila, which we reclassified as a separate species C. thermophila. We analyzed morphology, growth kinetics, and transcriptomic profiles of flagellates cultivated at low (23°C) and elevated (34°C) temperature. When maintained at high temperature, they grew significantly faster, became shorter, with genes involved in sugar metabolism and mitochondrial stres ...[more]