Ontology highlight
ABSTRACT:
SUBMITTER: Leake J
PROVIDER: S-EPMC5362699 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Leake Jessica J Zinn Raphael R Corbit Laura L Vissel Bryce B
Learning & memory (Cold Spring Harbor, N.Y.) 20170315 4
Rodents require a minimal time period to explore a context prior to footshock to display plateau-level context fear at test. To investigate whether this rapid fear plateau reflects complete memory formation within that short time-frame, we used the immediate-early gene product Arc as an indicator of hippocampal context memory formation-related activity. We found that hippocampal Arc expression continued to increase well past the minimal time required for plateau-level fear. This raises the possi ...[more]