Ontology highlight
ABSTRACT:
SUBMITTER: Hu W
PROVIDER: S-EPMC5363523 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Hu Weiping W Niu Guodong G Li Hongbo H Gao Hanyuan H Kang Rudian R Chen Xiaoqing X Lin Ling L
Oncotarget 20161101 47
Renal damage is the major cause of SLE associated mortality, and IFIT1expression was elevated in SLE cases in accordance of previous studies. Therefore, we conducted an animal study to identify the role of IFIT1 expression in renal pathological changes.18 female MRL/lpr mice and same number of female BALB/c mice were enrolled in present study. Quantitative analysis of urine protein, Complement C3 and C4, and anti-ds DNA antibody were conducted. HE and PAS staining and TEM analysis were employed ...[more]