Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC5363836 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Zhang Yan Y Zhang Rong R Ding Xixi X Peng Bangan B Wang Ning N Ma Fang F Peng Youmei Y Wang Qingduan Q Chang Junbiao J
PloS one 20170323 3
FNC, 2'-deoxy-2'-β-fluoro-4'-azidocytidine, is a novel cytidine analogue, that has shown strong antiproliferative activity in human lymphoma, lung adenocarcinoma and acute myeloid leukemia. In this study, we investigated the effects of FNC on mantle cell lymphoma (MCL) and the underlying mechanisms. In in vitro experiments, cell viability was detected by the CCK8 assay, and cell cycle progression and apoptosis were assessed by flow cytometry, and the expression of relative apoptosis proteins wer ...[more]