Ontology highlight
ABSTRACT:
SUBMITTER: Xu S
PROVIDER: S-EPMC5364407 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Xu Shicai S Zhan Jian J Man Baoyuan B Jiang Shouzhen S Yue Weiwei W Gao Shoubao S Guo Chengang C Liu Hanping H Li Zhenhua Z Wang Jihua J Zhou Yaoqi Y
Nature communications 20170321
Reliable determination of binding kinetics and affinity of DNA hybridization and single-base mismatches plays an essential role in systems biology, personalized and precision medicine. The standard tools are optical-based sensors that are difficult to operate in low cost and to miniaturize for high-throughput measurement. Biosensors based on nanowire field-effect transistors have been developed, but reliable and cost-effective fabrication remains a challenge. Here, we demonstrate that a graphene ...[more]