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High-throughput sequencing of pituitary and hypothalamic microRNA transcriptome associated with high rate of egg production.


ABSTRACT: MicroRNAs exist widely in viruses, plants and animals. As endogenous small non-coding RNAs, miRNAs regulate a variety of biological processes. Tissue miRNA expression studies have discovered numerous functions for miRNAs in various tissues of chicken, but the regulation of miRNAs in chicken pituitary and hypothalamic development related to high and low egg-laying performance has remained unclear.In this study, using high-throughput sequencing technology, we sequenced two tissues (pituitary and hypothalamus) in 3 high- and 3 low-rate egg production Luhua chickens at the age of 300 days. By comparing low- and high-rate egg production chickens, 46 known miRNAs and 27 novel miRNAs were identified as differentially expressed (P?

SUBMITTER: Wu N 

PROVIDER: S-EPMC5364632 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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High-throughput sequencing of pituitary and hypothalamic microRNA transcriptome associated with high rate of egg production.

Wu Nan N   Zhu Qing Q   Chen Binlong B   Gao Jian J   Xu Zhongxian Z   Li Diyan D   Li Diyan D  

BMC genomics 20170323 1


<h4>Background</h4>MicroRNAs exist widely in viruses, plants and animals. As endogenous small non-coding RNAs, miRNAs regulate a variety of biological processes. Tissue miRNA expression studies have discovered numerous functions for miRNAs in various tissues of chicken, but the regulation of miRNAs in chicken pituitary and hypothalamic development related to high and low egg-laying performance has remained unclear.<h4>Results</h4>In this study, using high-throughput sequencing technology, we seq  ...[more]

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