Ontology highlight
ABSTRACT:
SUBMITTER: Castrellon AB
PROVIDER: S-EPMC5365000 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Castrellon Aurelio Bartolome AB Pidhorecky Ihor I Valero Vicente V Raez Luis Estuardo LE
Oncology reviews 20170317 1
Triple negative breast (TNBC) cancer constitutes a heterogeneous group of disease with histologic and molecular differences. Complete pathologic response to neoadjuvant chemotherapy (NACT) in TNBC is associated with improved outcomes. Efforts have been made in identifying drug combinations that will increase the response rate to preoperative chemotherapy. In this review we present recent studies that have incorporated carboplatin (Cb) in the NACT of TNBC. We discuss the homologous recombination ...[more]