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Detection of the mcr-1 Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient.

ABSTRACT: Since colistin resistance based on the plasmid-encoded mcr-1 gene was first described, this resistance gene in Enterobacteriaceae has been found worldwide. These organisms are typically of heterogeneous genetic background and show exceptional clonal diversity. We describe the first confirmation of mcr-1 in a human Escherichia coli strain cultured from a surveillance stool sample of an Austrian oncology patient.

SUBMITTER: Hartl R

PROVIDER: S-EPMC5365693 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

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Detection of the mcr-1 Gene in a Multidrug-Resistant Escherichia coli Isolate from an Austrian Patient.

Hartl Rainer R Kerschner Heidrun H Lepuschitz Sarah S Ruppitsch Werner W Allerberger Franz F Apfalter Petra P

Antimicrobial agents and chemotherapy 20170324 4

Since colistin resistance based on the plasmid-encoded mcr-1 gene was first described, this resistance gene in Enterobacteriaceae has been found worldwide. These organisms are typically of heterogeneous genetic background and show exceptional clonal diversity. We describe the first confirmation of mcr-1 in a human Escherichia coli strain cultured from a surveillance stool sample of an Austrian oncology patient. ...[more]

PMID: 28137802

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