Ontology highlight
ABSTRACT:
SUBMITTER: Le CF
PROVIDER: S-EPMC5365711 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20170324 4
Antimicrobial peptides (AMPs) are expressed in various living organisms as first-line host defenses against potential harmful encounters in their surroundings. AMPs are short polycationic peptides exhibiting various antimicrobial activities. The principal antibacterial activity is attributed to the membrane-lytic mechanism which directly interferes with the integrity of the bacterial cell membrane and cell wall. In addition, a number of AMPs form a transmembrane channel in the membrane by self-a ...[more]