MAOA rs1137070 and heroin addiction interactively alter gray matter volume of the salience network.
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ABSTRACT:
SUBMITTER: Sun Y
PROVIDER: S-EPMC5366902 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
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MAOA rs1137070 and heroin addiction interactively alter gray matter volume of the salience network.
Sun Yan Y Liu Linwen L Feng Jiajia J Yue Weihua W Lu Lin L Fan Yong Y Shi Jie J
Scientific reports 20170327
The rs1137070 polymorphism of monoamine oxidase A (MAOA) is associated with alcoholism and smoking behavior. However, the association between rs1137070 and heroin addiction remains unclear. In this study, we examined the allelic distribution of rs1137070 in 1,035 heroin abusers and 2,553 healthy controls and investigated the interactive effects of rs1137070 and heroin addiction on gray matter volume (GMV) based on 78 heroin abusers and 79 healthy controls. The C allele frequency of rs1137070 was ...[more]
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