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Significant Decrease in Pertactin-Deficient Bordetella pertussis Isolates, Japan.


ABSTRACT: Prevalence of pertactin-lacking Bordetella pertussis isolates has been observed worldwide. In Japan, however, we found that the frequency of pertactin-deficient isolates in 2014-2016 (8%) was significantly lower than the frequency in 2005-2007 (41%), 2008-2010 (35%), and 2011-2013 (25%). This reduction was closely associated with changes in genotypes.

SUBMITTER: Hiramatsu Y 

PROVIDER: S-EPMC5367402 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

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Significant Decrease in Pertactin-Deficient Bordetella pertussis Isolates, Japan.

Hiramatsu Yukihiro Y   Miyaji Yusuke Y   Otsuka Nao N   Arakawa Yoshichika Y   Shibayama Keigo K   Kamachi Kazunari K  

Emerging infectious diseases 20170401 4


Prevalence of pertactin-lacking Bordetella pertussis isolates has been observed worldwide. In Japan, however, we found that the frequency of pertactin-deficient isolates in 2014-2016 (8%) was significantly lower than the frequency in 2005-2007 (41%), 2008-2010 (35%), and 2011-2013 (25%). This reduction was closely associated with changes in genotypes. ...[more]

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