Ontology highlight
ABSTRACT:
SUBMITTER: Arathoon E
PROVIDER: S-EPMC5367767 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
SAGE open medicine 20170118
<h4>Objective</h4>VIOLIN (TMC125IFD3002; NCT01422330) evaluated the safety, tolerability, and pharmacokinetics of etravirine with antiretrovirals other than darunavir/ritonavir in HIV-1-infected patients.<h4>Methods</h4>In a 48-week, phase IV, single-arm, multicenter study, patients on prior antiretroviral therapy (⩾8 weeks) who needed to change regimen for virologic failure (viral load ⩾ 500 copies/mL) or simplification/adverse events (viral load < 50 copies/mL) received etravirine 200 mg bid w ...[more]