Ontology highlight
ABSTRACT:
SUBMITTER: Kawagoe R
PROVIDER: S-EPMC5369533 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Kawagoe Ryosuke R Takashima Ippei I Uchinomiya Shohei S Ojida Akio A
Chemical science 20160926 2
Hydropersulfide (R-SSH) is an important class of reactive sulfur species (RSS) involved in a variety of physiological processes in mammals. A fluorescent probe capable of real-time detection of hydropersulfide levels in living cells would be a versatile tool to elucidate its roles in cell signalling and redox homeostasis. In this paper, we report a ratiometric fluorescent probe for hydropersulfide sensing, based on a fluorescence resonance energy transfer (FRET) mechanism. This sensing mechanism ...[more]