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Metal-Organic Framework as a Protective Coating for Biodiagnostic Chips.


ABSTRACT: Zeolitic imidazolate framework-8 (ZIF-8) grown around antibodies anchored to plasmonic nanostructures serves as a protective layer to preserve the biorecognition ability of antibodies stored at room and elevated temperatures for several days. The biofunctionality of the ZIF-8-protected biochip can be restored by a simple water-rinsing step, making it highly convenient for use in point-of-care and resource-limited settings.

SUBMITTER: Wang C 

PROVIDER: S-EPMC5369648 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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Metal-Organic Framework as a Protective Coating for Biodiagnostic Chips.

Wang Congzhou C   Tadepalli Sirimuvva S   Luan Jingyi J   Liu Keng-Ku KK   Morrissey Jeremiah J JJ   Kharasch Evan D ED   Naik Rajesh R RR   Singamaneni Srikanth S  

Advanced materials (Deerfield Beach, Fla.) 20161207 7


Zeolitic imidazolate framework-8 (ZIF-8) grown around antibodies anchored to plasmonic nanostructures serves as a protective layer to preserve the biorecognition ability of antibodies stored at room and elevated temperatures for several days. The biofunctionality of the ZIF-8-protected biochip can be restored by a simple water-rinsing step, making it highly convenient for use in point-of-care and resource-limited settings. ...[more]

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